Sequential Analysis of Trans-SNARE Formation in Intracellular Membrane Fusion

SNARE complexes are required for membrane fusion in the endomembrane system. They contain coiled-coil bundles of four helices, three (Q(a), Q(b), and Q(c)) from target (t)-SNAREs and one (R) from the vesicular (v)-SNARE. NSF/Sec18 disrupts these cis-SNARE complexes, allowing reassembly of their subu...

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Autori principali: Alpadi, Kannan, Kulkarni, Aditya, Comte, Veronique, Reinhardt, Monique, Schmidt, Andrea, Namjoshi, Sarita, Mayer, Andreas, Peters, Christopher
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2012
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3260307/
https://ncbi.nlm.nih.gov/pubmed/22272185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1001243
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