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Accounting For Alignment Uncertainty in Phylogenomics

Uncertainty in multiple sequence alignments has a large impact on phylogenetic analyses. Little has been done to evaluate the quality of individual positions in protein sequence alignments, which directly impact the accuracy of phylogenetic trees. Here we describe ZORRO, a probabilistic masking prog...

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Bibliografiske detaljer
Main Authors: Wu, Martin, Chatterji, Sourav, Eisen, Jonathan A.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3260272/
https://ncbi.nlm.nih.gov/pubmed/22272325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0030288
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