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Histone hyperacetylation has little effect on the higher order folding of chromatin.
HeLa cells were grown in the presence of 10 mM sodium butyrate and soluble chromatin containing hyperacetylated histones was prepared by mild micrococcal nuclease digestion and sucrose gradient fractionation. Sedimentation and electric dichroism were used to study the cation-induced folding of this...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
1983
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| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC326025/ https://ncbi.nlm.nih.gov/pubmed/6866766 |
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