Reversible decatenation of kinetoplast DNA by a DNA topoisomerase from trypanosomatids.
DNA topoisomerase activity detected in cell extracts of the trypanosomatid Crithidia fasciculata interlocks kinetoplast DNA duplex minicircles into huge catenane forms resembling the natural kinetoplast DNA networks found in trypanosomes. Catenation of duplex DNA circles is reversible and equilibriu...
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| Veröffentlicht in: | Nucleic Acids Res |
|---|---|
| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
1983
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| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC326022/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6306572/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/11.12.4019 |
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