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Erythrocyte Inosine Triphosphatase Activity Is Decreased in HIV-Seropositive Individuals
BACKGROUND: Inosine triphosphatase (ITPase) is encoded by the polymorphic gene ITPA and maintains low intracellular levels of the inosine nucleotides ITP and dITP. The most frequently reported polymorphisms are ITPA c.94C>A (rs 1127354) and ITPA c. 124+21 A>C (rs7270101). Some nucleoside-analo...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3260219/ https://ncbi.nlm.nih.gov/pubmed/22272297 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0030175 |
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