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Disturbance of the OPG/RANK/RANKL pathway and systemic inflammation in COPD patients with emphysema and osteoporosis

BACKGROUND: Osteoporosis is one of the systemic features of COPD. A correlation between the emphysema phenotype of COPD and reduced bone mineral density (BMD) is suggested by some studies, however, the mechanisms underlying this relationship are unclear. Experimental studies indicate that IL-1β, IL-...

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Detalhes bibliográficos
Main Authors: Bai, Peng, Sun, Yongchang, Jin, Jianmin, Hou, Jia, Li, Ran, Zhang, Qing, Wang, Yang
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3260206/
https://ncbi.nlm.nih.gov/pubmed/22176920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-12-157
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