Genetic and functional evaluation of the role of CXCR1 and CXCR2 in susceptibility to visceral leishmaniasis in north-east India

BACKGROUND: IL8RA and IL8RB, encoded by CXCR1 and CXCR2, are receptors for interleukin (IL)-8 and other CXC chemokines involved in chemotaxis and activation of polymorphonuclear neutrophils (PMN). Variants at CXCR1 and CXCR2 have been associated with susceptibility to cutaneous and mucocutaneous lei...

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Main Authors: Mehrotra, Sanjana, Fakiola, Michaela, Oommen, Joyce, Jamieson, Sarra E, Mishra, Anshuman, Sudarshan, Medhavi, Tiwary, Puja, Rani, Deepa Selvi, Thangaraj, Kumarasamy, Rai, Madhukar, Sundar, Shyam, Blackwell, Jenefer M
Format: Artigo
Language:Inglês
Published: BioMed Central 2011
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3260103/
https://ncbi.nlm.nih.gov/pubmed/22171941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2350-12-162
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