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Angiopoeitin-2 Modulates Survivin Expression in OxLDL-Induced Endothelial Cell Apoptosis
Angiopoeitin-2 (Ang-2) antagonizes Angiopeitin-1 (Ang-1) -mediated Tie-2 signaling. Ang-1 is reported to up-regulate anti-apoptotic Survivin expression. Here, we investigated the interplay between Ang-2 and Survivin in response to oxidized low density lipoprotein (OxLDL)-induced apoptosis. We demons...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3260082/ https://ncbi.nlm.nih.gov/pubmed/22182412 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2011.12.018 |
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