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Is titin a ‘winding filament’? A new twist on muscle contraction

Recent studies have demonstrated a role for the elastic protein titin in active muscle, but the mechanisms by which titin plays this role remain to be elucidated. In active muscle, Ca(2+)-binding has been shown to increase titin stiffness, but the observed increase is too small to explain the increa...

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Библиографические подробности
Главные авторы: Nishikawa, Kiisa C., Monroy, Jenna A., Uyeno, Theodore E., Yeo, Sang Hoon, Pai, Dinesh K., Lindstedt, Stan L.
Формат: Artigo
Язык:Inglês
Опубликовано: The Royal Society 2012
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3259925/
https://ncbi.nlm.nih.gov/pubmed/21900329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rspb.2011.1304
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