Cysteine S-Nitrosylation Protects Protein-tyrosine Phosphatase 1B against Oxidation-induced Permanent Inactivation

Protein S-nitrosylation mediated by cellular nitric oxide (NO) plays a primary role in executing biological functions in cGMP-independent NO signaling. Although S-nitrosylation appears similar to Cys oxidation induced by reactive oxygen species, the molecular mechanism and biological consequence rem...

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Main Authors: Chen, Yi-Yun, Chu, Hsing-Mao, Pan, Kuan-Ting, Teng, Chun-Hung, Wang, Danny-Ling, Wang, Andrew H.-J., Khoo, Kay-Hooi, Meng, Tzu-Ching
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2008
Assuntos:
Protein Synthesis, Post-Translational Modification, and Degradation
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3259880/
https://ncbi.nlm.nih.gov/pubmed/18840608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M805287200
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