Analgesic Compound from Sea Anemone Heteractis crispa Is the First Polypeptide Inhibitor of Vanilloid Receptor 1 (TRPV1)

Venomous animals from distinct phyla such as spiders, scorpions, snakes, cone snails, or sea anemones produce small toxic proteins interacting with a variety of cell targets. Their bites often cause pain. One of the ways of pain generation is the activation of TRPV1 channels. Screening of 30 differe...

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Autors principals: Andreev, Yaroslav A., Kozlov, Sergey A., Koshelev, Sergey G., Ivanova, Ekaterina A., Monastyrnaya, Margarita M., Kozlovskaya, Emma P., Grishin, Eugene V.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2008
Matèries:
Protein Structure and Folding
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3259759/
https://ncbi.nlm.nih.gov/pubmed/18579526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M800776200
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