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Low humidity environmental challenge causes barrier disruption and cornification of the mouse corneal epithelium in mice via a c-jun N-terminal kinase 2 (JNK2) pathway

Patients with tear dysfunction often experience increased irritation symptoms when subjected to drafty and/or low humidity environmental conditions. The purpose of this study was to investigate the effects of low humidity stress (LHS) on corneal barrier function and expression of cornified envelope...

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Autores principales: Pelegrino, FSA, Pflugfelder, SC, De Paiva, CS
Formato: Artigo
Lenguaje:Inglês
Publicado: 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3259221/
https://ncbi.nlm.nih.gov/pubmed/22166618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2011.11.022
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