Electrophilic PPARγ ligands inhibit corneal fibroblast to myofibroblast differentiation in vitro: A potentially novel therapy for corneal scarring

A critical component of corneal scarring is the TGFβ-induced differentiation of corneal keratocytes into myofibroblasts. Inhibitors of this differentiation are potentially therapeutic for corneal scarring. In this study, we tested the relative effectiveness and mechanisms of action of two electrophi...

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Autori principali: Kuriyan, A.E., Lehmann, G.M., Kulkarni, A.A., Woeller, C.F., Feldon, S.E., Hindman, H.B., Sime, P., Huxlin, K.R., Phipps, R.P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3259184/
https://ncbi.nlm.nih.gov/pubmed/22178289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2011.11.018
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