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Regulation of hTERT by BCR-ABL at multiple levels in K562 cells
BACKGROUND: The cytogenetic characteristic of Chronic Myeloid Leukemia (CML) is the formation of the Philadelphia chromosome gene product, BCR-ABL. Given that BCR-ABL is the specific target of Gleevec in CML treatment, we investigated the regulation of the catalytic component of telomerase, hTERT, b...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
BioMed Central
2011
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3259104/ https://ncbi.nlm.nih.gov/pubmed/22151181 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-11-512 |
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