A non-synonymous coding change in the CYP19A1 gene Arg264Cys (rs700519) does not affect circulating estradiol, bone structure or fracture

BACKGROUND: The biosynthesis of estrogens from androgens is catalyzed by aromatase P450 enzyme, coded by the CYP19A1 gene on chromosome 15q21.2. Genetic variation within the CYP19A1 gene sequence has been shown to alter the function of the enzyme. The aim of this study is to investigate whether a no...

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Bibliografiska uppgifter
Huvudupphovsmän: Wang, Jenny Z, Deogan, Mandeep S, Lewis, Joshua R, Chew, Shelby, Mullin, Ben H, McNab, Tegan J, Wilson, Scott G, Ingley, Evan, Prince, Richard L
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2011
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3259055/
https://ncbi.nlm.nih.gov/pubmed/22185650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2350-12-165
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