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Effects of thyroid hormone analogue and a leukotrienes pathway-blocker on renal ischemia/reperfusion injury in mice

BACKGROUND: Acute renal failure (ARF) is an important clinical problem with a high mortality and morbidity. One of the primary causes of ARF is ischemia/reperfusion (I/R). Inflammatory process and oxidative stress are thought to be the major mechanisms causing I/R. MK-886 is a potent inhibitor of le...

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Detalhes bibliográficos
Main Authors: Hadi, Najah R, Al-amran, Fadhil G, Hussein, Ayad A
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3259032/
https://ncbi.nlm.nih.gov/pubmed/22196041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2369-12-70
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