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Whirlin interacts with espin and modulates its actin-regulatory function: an insight into the mechanism of Usher syndrome type II

Whirlin mutations cause retinal degeneration and hearing loss in Usher syndrome type II (USH2) and non-syndromic deafness, DFNB31. Its protein recruits other USH2 causative proteins to form a complex at the periciliary membrane complex in photoreceptors and the ankle link of the stereocilia in hair...

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Hlavní autoři: Wang, Le, Zou, Junhuang, Shen, Zuolian, Song, E., Yang, Jun
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3259019/
https://ncbi.nlm.nih.gov/pubmed/22048959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddr503
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