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Phactr4 regulates directional migration of enteric neural crest through PP1, integrin signaling, and cofilin activity
Hirschsprung disease (HSCR) is caused by a reduction of enteric neural crest cells (ENCCs) in the gut and gastrointestinal blockage. Knowledge of the genetics underlying HSCR is incomplete, particularly genes that control cellular behaviors of ENCC migration. Here we report a novel regulator of ENCC...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2012
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3258968/ https://ncbi.nlm.nih.gov/pubmed/22215812 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.179283.111 |
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