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Phactr4 regulates directional migration of enteric neural crest through PP1, integrin signaling, and cofilin activity

Hirschsprung disease (HSCR) is caused by a reduction of enteric neural crest cells (ENCCs) in the gut and gastrointestinal blockage. Knowledge of the genetics underlying HSCR is incomplete, particularly genes that control cellular behaviors of ENCC migration. Here we report a novel regulator of ENCC...

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Detalhes bibliográficos
Main Authors: Zhang, Ying, Kim, Tae-Hee, Niswander, Lee
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3258968/
https://ncbi.nlm.nih.gov/pubmed/22215812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.179283.111
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