Spatial arrangement of an RNA zipcode identifies mRNAs under post-transcriptional control

How RNA-binding proteins recognize specific sets of target mRNAs remains poorly understood because current approaches depend primarily on sequence information. In this study, we demonstrate that specific recognition of messenger RNAs (mRNAs) by RNA-binding proteins requires the correct spatial posit...

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Autors principals: Patel, Vivek L., Mitra, Somdeb, Harris, Richard, Buxbaum, Adina R., Lionnet, Timothée, Brenowitz, Michael, Girvin, Mark, Levy, Matthew, Almo, Steven C., Singer, Robert H., Chao, Jeffrey A.
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2012
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3258965/
https://ncbi.nlm.nih.gov/pubmed/22215810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.177428.111
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