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Purification of genomic sequences from bacteriophage libraries by recombination and selection in vivo.

Cloned genes have been purified from recombinant DNA bacteriophage libraries by a method exploiting homologous reciprocal recombination in vivo. In this method 'probe' sequences are inserted in a very small plasmid vector and introduced into recombination-proficient bacterial cells. Genomi...

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Bibliographic Details
Main Author: Seed, B
Format: Artigo
Language:Inglês
Published: 1983
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC325894/
https://ncbi.nlm.nih.gov/pubmed/6856467
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