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Rho/Rho-associated Kinase Signal Regulates Myogenic Differentiation via Myocardin-related Transcription Factor-A/Smad-dependent Transcription of the Id3 Gene

RhoA is known to be involved in myogenic differentiation, but whether it acts as a positive or negative regulator is controversial. To resolve this issue, we investigated the differentiation stage-specific roles of RhoA and its effector, Rho-associated kinase, using C2C12 myoblasts. We found that pr...

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Detalhes bibliográficos
Main Authors: Iwasaki, Kazuhiro, Hayashi, Ken'ichiro, Fujioka, Tomoaki, Sobue, Kenji
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3258938/
https://ncbi.nlm.nih.gov/pubmed/18477564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M710525200
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