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Contribution of Redox Status to Hepatitis C Virus E2 Envelope Protein Function and Antigenicity

Disulfide bonding contributes to the function and antigenicity of many viral envelope glycoproteins. We assessed here its significance for the hepatitis C virus E2 envelope protein and a counterpart deleted for hypervariable region-1 (HVR1). All 18 cysteine residues of the antigens were involved in...

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Detalhes bibliográficos
Main Authors: Fenouillet, Emmanuel, Lavillette, Dimitri, Loureiro, Silvia, Krashias, George, Maurin, Guillemette, Cosset, François-Loïc, Jones, Ian M., Barbouche, Rym
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3258924/
https://ncbi.nlm.nih.gov/pubmed/18667425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M805221200
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