Phosphorylation and Ankyrin-G Binding of the C-terminal Domain Regulate Targeting and Function of the Ammonium Transporter RhBG

RhBG, a human member of the Amt/Mep/Rh/superfamily of ammonium transporters, has been shown to facilitate NH(3) transport and to be anchored to the basolateral plasma membrane of kidney epithelial cells, via ankyrin-G. We showed here that triple alanine substitution of the (419)FLD(421) sequence, wh...

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Bibliographische Detailangaben
Hauptverfasser: Sohet, Fabien, Colin, Yves, Genetet, Sandrine, Ripoche, Pierre, Métral, Sylvain, Le Van Kim, Caroline, Lopez, Claude
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2008
Schlagworte:
Protein Synthesis, Post-Translational Modification, and Degradation
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3258915/
https://ncbi.nlm.nih.gov/pubmed/18635543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M803120200
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