The Caenorhabditis elegans AMP-activated Protein Kinase AAK-2 Is Phosphorylated by LKB1 and Is Required for Resistance to Oxidative Stress and for Normal Motility and Foraging Behavior

AAK-2 is one of two α isoforms of the AMP-activated protein kinase in Caenorhabditis elegans and is involved in life span maintenance, stress responses, and germ cell cycle arrest upon dauer entry. We found that AAK-2 was phosphorylated at threonine 243 in response to paraquat treatment and that thi...

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Detalhes bibliográficos
Main Authors: Lee, Hyojin, Cho, Jeong Soo, Lambacher, Nils, Lee, Jieun, Lee, Se-Jin, Lee, Tae Hoon, Gartner, Anton, Koo, Hyeon-Sook
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
Assuntos:
Molecular Basis of Cell and Developmental Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3258889/
https://ncbi.nlm.nih.gov/pubmed/18408008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M709115200
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