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Ribosome Performance Is Enhanced by a Rich Cluster of Pseudouridines in the A-site Finger Region of the Large Subunit
The large subunit rRNA in eukaryotes contains an unusually dense cluster of 8–10 pseudouridine (Ψ) modifications located in a three-helix structure (H37–H39) implicated in several functions. This region is dominated by a long flexible helix (H38) known as the “A-site finger” (ASF). The ASF protrudes...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3258867/ https://ncbi.nlm.nih.gov/pubmed/18611858 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M803049200 |
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