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Nuclear matrix-DNA complex resulting from EcoR1 digestion of HeLa nucleoids is enriched for DNA replicating forks

Upon treatment of HeLa nucleoids with EcoR1 restriction enzyme, a minute fraction of the DNA remains attached to the nuclear matrix. This matrix-DNA complex appears to be composed of a unique set of proteins. Electron microscopic analysis of the DNA fragments present shows an enrichment for HeLa DNA...

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Main Authors: Valenzuela, Manuel S., Mueller, Gerald C., Dasgupta, Santanu
Formato: Artigo
Idioma:Inglês
Publicado: 1983
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC325868/
https://ncbi.nlm.nih.gov/pubmed/6300795
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