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d-Amino acid oxidase controls motoneuron degeneration through d-serine
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder involving an extensive loss of motoneurons. Aberrant excitability of motoneurons has been implicated in the pathogenesis of selective motoneuronal death in ALS. d-Serine, an endogenous coagonist of N-methyl-d-aspartate recepto...
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| Hauptverfasser: | , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3258611/ https://ncbi.nlm.nih.gov/pubmed/22203986 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1114639109 |
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