Hepatocyte growth factor (HGF) autocrine activation predicts sensitivity to MET inhibition in glioblastoma

Because oncogene MET and EGF receptor (EGFR) inhibitors are in clinical development against several types of cancer, including glioblastoma, it is important to identify predictive markers that indicate patient subgroups suitable for such therapies. We investigated in vivo glioblastoma models charact...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Xie, Qian, Bradley, Robert, Kang, Liang, Koeman, Julie, Ascierto, Maria Libera, Worschech, Andrea, De Giorgi, Valeria, Wang, Ena, Kefene, Lisa, Su, Yanli, Essenburg, Curt, Kaufman, Dafna W., DeKoning, Tom, Enter, Mark A., O'Rourke, Timothy J., Marincola, Francesco M., Vande Woude, George F.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2012
Pynciau:
Biological Sciences
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3258605/
https://ncbi.nlm.nih.gov/pubmed/22203985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1119059109
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