CD4(+) CD25(+) Foxp3(+) regulatory T cells promote Th17 cells in vitro and enhance host resistance in mouse Candida albicans Th17 cell infection model

Th17 cells and CD4(+)CD25(+)Foxp3(+) regulatory T (Treg) cells are thought to promote and suppress inflammatory responses, respectively. Here we explore why under Th17 cell conditions, Treg cells did not suppress, but rather up-regulated the expression of interleukin-17A (IL-17A), IL-17F and IL-22 f...

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Autors principals: Pandiyan, Pushpa, Conti, Heather R., Zheng, Lixin, Peterson, Alanna C., Mathern, Douglas R., Hernández-Santos, Nydiaris, Edgerton, Mira, Gaffen, Sarah L., Lenardo, Michael J.
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3258585/
https://ncbi.nlm.nih.gov/pubmed/21435589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2011.03.002
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