Departures from the Protocol During Conduct of a Clinical Trial: A Pattern from the Data Record Consistent with a Learning Curve

OBJECTIVE: Recognition of learning curves in medical skill acquisition has enhanced patient safety through improved training techniques. Clinical trials research has not been similarly scrutinized. We retrospectively evaluated VALIANT, a large multinational, pragmatic, randomized, double-blind, mult...

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Detalhes bibliográficos
Main Authors: Taekman, Jeffrey M., Stafford-Smith, Mark, Velazquez, Eric J., Wright, Melanie C., Phillips-Bute, Barbara G., Pfeffer, Marc A., Ann Sellers, Mary, Pieper, Karen S., Newman, Mark F., Van de Werf, Frans, Diaz, Rafael, Leimberger, Jeff, Califf, Robert M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3258507/
https://ncbi.nlm.nih.gov/pubmed/20702441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/qshc.2008.028605
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