Pathogen-derived effectors trigger protective immunity via activation of the Rac2 enzyme and the IMD or Rip kinase signaling pathway

Although infections with virulent pathogens often induce a strong inflammatory reaction, what drives the increased immune response to pathogens compared to non-pathogenic microbes is poorly understood. One possibility is that the immune system senses the level of threat from a microorganism and augm...

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Autores principales: Boyer, Laurent, Magoc, Lorin, Dejardin, Stephanie, Cappillino, Michael, Paquette, Nicholas, Hinault, Charlotte, Charriere, Guillaume M., Ip, WK Eddie, Fracchia, Shannon, Hennessy, Elizabeth, Erturk-Hasdemir, Deniz, Reichhart, Jean-Marc, Silverman, Neal, Lacy-Hulbert, Adam, Stuart, Lynda M.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2011
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3258503/
https://ncbi.nlm.nih.gov/pubmed/22018470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2011.08.015
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