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An Allenic Pauson–Khand Approach to 6,12-Guaianolides

[Image: see text] Cyclocarbonylation of α-methylene butyrolactone-containing allene-ynes affords 6,12-guaianolide ring systems. Incorporation of the α-methylene butyrolactone early in a synthetic sequence is rare for reactivity reasons; however, this moiety proves to be beneficial to the allenic Pau...

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Autors principals: Grillet, Francois, Huang, Chaofeng, Brummond, Kay M.
Format: Artigo
Idioma:Inglês
Publicat: 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3258445/
https://ncbi.nlm.nih.gov/pubmed/22070869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol2028515
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