Multiple Sclerosis Risk Variant HLA-DRB1*1501 Associates with High Expression of DRB1 Gene in Different Human Populations

The human leukocyte antigen (HLA) DRB1*1501 has been consistently associated with multiple sclerosis (MS) in nearly all populations tested. This points to a specific antigen presentation as the pathogenic mechanism though this does not fully explain the disease association. The identification of exp...

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Bibliographic Details
Main Authors:	Alcina, Antonio, Abad-Grau, María del Mar, Fedetz, María, Izquierdo, Guillermo, Lucas, Miguel, Fernández, Óscar, Ndagire, Dorothy, Catalá-Rabasa, Antonio, Ruiz, Agustín, Gayán, Javier, Delgado, Concepción, Arnal, Carmen, Matesanz, Fuencisla
Format:	Artigo
Language:	Inglês
Published:	Public Library of Science 2012
Subjects:	Research Article
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC3258250/ https://ncbi.nlm.nih.gov/pubmed/22253788 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0029819
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Multiple Sclerosis Risk Variant HLA-DRB1*1501 Associates with High Expression of DRB1 Gene in Different Human Populations

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