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Grape seed proanthocyanidins inhibit the invasive potential of head and neck cutaneous squamous cell carcinoma cells by targeting EGFR expression and epithelial-to-mesenchymal transition

BACKGROUND: Head and neck squamous cell carcinoma (HNSCC) is responsible for over 20,000 deaths every year in United States. Most of the deaths are due, in large part, to its propensity to metastasize. We have examined the effect of bioactive component grape seed proanthocyanidins (GSPs) on human cu...

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Autors principals: Sun, Qian, Prasad, Ram, Rosenthal, Eben, Katiyar, Santosh K
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3258217/
https://ncbi.nlm.nih.gov/pubmed/22188922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6882-11-134
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