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Punctuated cyclin synthesis drives early embryonic cell cycle oscillations

Cyclin B activates cyclin-dependent kinase 1 (CDK1) at mitosis, but conflicting views have emerged on the dynamics of its synthesis during embryonic cycles, ranging from continuous translation to rapid synthesis during mitosis. Here we show that a CDK1-mediated negative-feedback loop attenuates cycl...

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Detaylı Bibliyografya
Asıl Yazarlar: Kang, Qing, Pomerening, Joseph R.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The American Society for Cell Biology 2012
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3258173/
https://ncbi.nlm.nih.gov/pubmed/22130797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E11-09-0768
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