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Novel reporter systems for facile evaluation of I-SceI-mediated genome editing

Two major limitations to achieve efficient homing endonuclease-stimulated gene correction using retroviral vectors are low frequency of gene targeting and random integration of the targeting vectors. To overcome these issues, we developed a reporter system for quick and facile testing of novel strat...

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Bibliografische gegevens
Hoofdauteurs: Muñoz, Nina M., Beard, Brian C., Ryu, Byoung Y., Luche, Ralf M., Trobridge, Grant D., Rawlings, David J., Scharenberg, Andrew M., Kiem, Hans-Peter
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2012
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3258163/
https://ncbi.nlm.nih.gov/pubmed/22110042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr897
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