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Transcriptional activation by mitochondrial transcription factor A involves preferential distortion of promoter DNA

Mitochondrial transcription factor A (mtTFA/TFAM) is a nucleus-encoded, high-mobility-group-box (HMG-box) protein that regulates transcription of the mitochondrial genome by specifically recognizing light-strand and heavy-strand promoters (LSP, HSP1). TFAM also binds mitochondrial DNA in a non-seque...

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Detalhes bibliográficos
Main Authors: Malarkey, Christopher S., Bestwick, Megan, Kuhlwilm, Jane E., Shadel, Gerald S., Churchill, Mair E. A.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3258160/
https://ncbi.nlm.nih.gov/pubmed/21948790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr787
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