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The human translation initiation multi-factor complex promotes methionyl-tRNA(i) binding to the 40S ribosomal subunit

The delivery of Met-tRNA(i) to the 40S ribosomal subunit is thought to occur by way of a ternary complex (TC) comprising eIF2, GTP and Met-tRNA(i). We have generated from purified human proteins a stable multifactor complex (MFC) comprising eIF1, eIF2, eIF3 and eIF5, similar to the MFC reported in y...

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Autors principals: Sokabe, Masaaki, Fraser, Christopher S., Hershey, John W. B.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2012
Matèries:
RNA
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3258154/
https://ncbi.nlm.nih.gov/pubmed/21940399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr772
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