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MiR-145 directly targets p70S6K1 in cancer cells to inhibit tumor growth and angiogenesis

MiR-145 can regulate cell apoptosis, proliferation, neural development and stem cell differentiation. Previous studies indicate that miR-145 is downregulated in human colon cancer cells. However, the molecular mechanisms of miR-145 used to regulate colon carcinogenesis and angiogenesis remain to be...

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Detalhes bibliográficos
Main Authors: Xu, Qing, Liu, Ling-Zhi, Qian, Xu, Chen, Qi, Jiang, Yue, Li, Dan, Lai, Lihui, Jiang, Bing-Hua
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3258133/
https://ncbi.nlm.nih.gov/pubmed/21917858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr730
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