The Deubiquitinase Activity of the Salmonella Pathogenicity Island 2 Effector, SseL, Prevents Accumulation of Cellular Lipid Droplets

To cause disease, Salmonella enterica serovar Typhimurium requires two type III secretion systems that are encoded by Salmonella pathogenicity islands 1 and 2 (SPI-1 and -2). These secretion systems serve to deliver specialized proteins (effectors) into the host cell cytosol. While the importance of...

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Bibliographic Details
Main Authors: Arena, Ellen T., Auweter, Sigrid D., Antunes, L. Caetano M., Vogl, A. Wayne, Han, Jun, Guttman, Julian A., Croxen, Matthew A., Menendez, Alfredo, Covey, Scott D., Borchers, Christoph H., Finlay, B. Brett
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2011
Subjects:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3257934/
https://ncbi.nlm.nih.gov/pubmed/21875964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.05478-11
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