Inhibition of Indoleamine 2,3-Dioxygenase Activity by Levo-1-Methyl Tryptophan Blocks Gamma Interferon-Induced Chlamydia trachomatis Persistence in Human Epithelial Cells

Gamma interferon (IFN-γ) induces expression of the tryptophan-catabolizing enzyme indoleamine 2,3-dioxygenase (IDO1) in human epithelial cells, the permissive cells for the obligate intracellular bacterium Chlamydia trachomatis. IDO1 depletes tryptophan by catabolizing it to kynurenine with conseque...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Ibana, Joyce A., Belland, Robert J., Zea, Arnold H., Schust, Danny J., Nagamatsu, Takeshi, AbdelRahman, Yasser M., Tate, David J., Beatty, Wandy L., Aiyar, Ashok A., Quayle, Alison J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3257928/
https://ncbi.nlm.nih.gov/pubmed/21911470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.05659-11
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados