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Proteases and sFlt-1 release in the human placenta

Increased placental release of soluble VEGF receptor-1 (sFlt-1) is believed to play an important role in the pathogenesis of preeclampsia (PE). Although the reason for increased placental sFlt-1 release in PE is unknown, proteolytic effect has been proposed as one of the mechanisms that mediate sFlt...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Zhao, Shuang, Gu, Yang, Fan, Ruping, Groome, Lynn J., Cooper, Danielle, Wang, Yuping
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3257833/
https://ncbi.nlm.nih.gov/pubmed/20434767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.placenta.2010.03.014
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