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A convenient synthesis of 6-amino-1-beta-D-ribofuranosylpyrazolo[3,4-d]pyrimidin-4-one and related 4,6-disubstituted pyrazolopyrimidine nucleosides.

The glycosylation of 4,6-dichloropyrazolo[3,4-d]pyrimidine and 4-chloro-6-methylthiopyrazolo[3,4-d]pyrimidine via the corresponding trimethylsilyl intermediate and tetra-O-acetyl-beta-D-ribofuranose in the presence of trimethylsilyl triflate as a catalyst, gave selective glycosylation at N1 as the o...

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Detalhes bibliográficos
Main Authors: Cottam, H B, Revankar, G R, Robins, R K
Formato: Artigo
Idioma:Inglês
Publicado em: 1983
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC325758/
https://ncbi.nlm.nih.gov/pubmed/6835838
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