Ajuba is required for Rac activation and maintenance of E-cadherin adhesion

Maintenance of stable E-cadherin–dependent adhesion is essential for epithelial function. The small GTPase Rac is activated by initial cadherin clustering, but the precise mechanisms underlying Rac-dependent junction stabilization are not well understood. Ajuba, a LIM domain protein, colocalizes wit...

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Bibliografiske detaljer
Main Authors: Nola, Sébastien, Daigaku, Reiko, Smolarczyk, Kasia, Carstens, Maryke, Martin-Martin, Belen, Longmore, Gregory, Bailly, Maryse, Braga, Vania M.M.
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2011
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3257575/
https://ncbi.nlm.nih.gov/pubmed/22105346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201107162
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