E–N-cadherin heterodimers define novel adherens junctions connecting endoderm-derived cells

Intercellular junctions play a pivotal role in tissue development and function and also in tumorigenesis. In epithelial cells, decrease or loss of E-cadherin, the hallmark molecule of adherens junctions (AJs), and increase of N-cadherin are widely thought to promote carcinoma progression and metasta...

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Detalhes bibliográficos
Main Authors: Straub, Beate K., Rickelt, Steffen, Zimbelmann, Ralf, Grund, Christine, Kuhn, Caecilia, Iken, Marcus, Ott, Michael, Schirmacher, Peter, Franke, Werner W.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2011
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3257573/
https://ncbi.nlm.nih.gov/pubmed/22105347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201106023
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