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Crumbs regulates rhodopsin transport by interacting with and stabilizing myosin V
The evolutionarily conserved Crumbs (Crb) complex is crucial for photoreceptor morphogenesis and homeostasis. Loss of Crb results in light-dependent retinal degeneration, which is prevented by feeding mutant flies carotenoid-deficient medium. This suggests a defect in rhodopsin 1 (Rh1) processing, t...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
The Rockefeller University Press
2011
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3257572/ https://ncbi.nlm.nih.gov/pubmed/22105348 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201105144 |
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