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Crumbs regulates rhodopsin transport by interacting with and stabilizing myosin V

The evolutionarily conserved Crumbs (Crb) complex is crucial for photoreceptor morphogenesis and homeostasis. Loss of Crb results in light-dependent retinal degeneration, which is prevented by feeding mutant flies carotenoid-deficient medium. This suggests a defect in rhodopsin 1 (Rh1) processing, t...

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Detalhes bibliográficos
Main Authors: Pocha, Shirin Meher, Shevchenko, Anna, Knust, Elisabeth
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3257572/
https://ncbi.nlm.nih.gov/pubmed/22105348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201105144
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