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Actin filaments function as a tension sensor by tension-dependent binding of cofilin to the filament

Intracellular and extracellular mechanical forces affect the structure and dynamics of the actin cytoskeleton. However, the underlying molecular and biophysical mechanisms, including how mechanical forces are sensed, are largely unknown. Actin-depolymerizing factor/cofilin proteins are actin-modulat...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Hayakawa, Kimihide, Tatsumi, Hitoshi, Sokabe, Masahiro
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3257564/
https://ncbi.nlm.nih.gov/pubmed/22123860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201102039
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