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Actin filaments function as a tension sensor by tension-dependent binding of cofilin to the filament

Intracellular and extracellular mechanical forces affect the structure and dynamics of the actin cytoskeleton. However, the underlying molecular and biophysical mechanisms, including how mechanical forces are sensed, are largely unknown. Actin-depolymerizing factor/cofilin proteins are actin-modulat...

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Detalhes bibliográficos
Main Authors: Hayakawa, Kimihide, Tatsumi, Hitoshi, Sokabe, Masahiro
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3257564/
https://ncbi.nlm.nih.gov/pubmed/22123860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201102039
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