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An intramolecular salt bridge drives the soluble domain of GTP-bound atlastin into the postfusion conformation

Endoplasmic reticulum (ER) network branching requires homotypic tethering and fusion of tubules mediated by the atlastin (ATL) guanosine triphosphatase (GTPase). Recent structural studies on the ATL soluble domain reveal two dimeric conformers proposed to correspond to a tethered prefusion state and...

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Detalhes bibliográficos
Main Authors: Morin-Leisk, Jeanne, Saini, Simran G., Meng, Xin, Makhov, Alexander M., Zhang, Peijun, Lee, Tina H.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3257528/
https://ncbi.nlm.nih.gov/pubmed/22065636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201105006
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