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Parsimonious Higher-Order Hidden Markov Models for Improved Array-CGH Analysis with Applications to Arabidopsis thaliana

Array-based comparative genomic hybridization (Array-CGH) is an important technology in molecular biology for the detection of DNA copy number polymorphisms between closely related genomes. Hidden Markov Models (HMMs) are popular tools for the analysis of Array-CGH data, but current methods are only...

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Detalhes bibliográficos
Main Authors: Seifert, Michael, Gohr, André, Strickert, Marc, Grosse, Ivo
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3257270/
https://ncbi.nlm.nih.gov/pubmed/22253580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1002286
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