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Solid phase synthesis of polynucleotides. VIII. Synthesis of mixed oligodeoxyribonucleotides by the phosphotriester solid phase method.

A solid phase method for the simultaneous synthesis of mixed oligonucleotides using a phosphotriester approach has been developed. For this synthesis, a mixture of mono or dimeric coupling units is used, and a slight difference in the reactivity of those units is found. However, this difference does...

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Autors principals: Ike, Y, Ikuta, S, Sato, M, Huang, T, Itakura, K
Format: Artigo
Idioma:Inglês
Publicat: 1983
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC325727/
https://ncbi.nlm.nih.gov/pubmed/6828376
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